Sun-Mi Yun Selected Research

5- ((6- phenyl- (1,2,4)triazolo(4,3- b)pyridazin- 3- yl)methyl)isoquinolin- 1(2H)- one

5/2013

KRC-327, a selective novel inhibitor of c-Met receptor tyrosine kinase with anticancer activity.

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Sun-Mi Yun Research Topics

Disease

14	Neoplasms (Cancer) 01/2020 - 11/2009
5	Breast Neoplasms (Breast Cancer) 02/2016 - 11/2009
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2014 - 07/2011
2	Carcinogenesis 01/2020 - 05/2013
2	Fibrosis (Cirrhosis) 01/2020 - 01/2019
2	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 03/2012
2	Hepatocellular Carcinoma (Hepatoma) 07/2013 - 02/2013
2	Prostatic Neoplasms (Prostate Cancer) 12/2010 - 01/2010
1	Colorectal Neoplasms (Colorectal Cancer) 03/2020
1	Colonic Neoplasms (Colon Cancer) 03/2020
1	Body Weight (Weight, Body) 03/2020
1	Fatty Liver 03/2020
1	Pathologic Constriction (Stenosis) 01/2019
1	Colitis 01/2018
1	Inflammation (Inflammations) 01/2018
1	Endometrial Neoplasms (Endometrial Cancer) 12/2017
1	Leukemia 03/2014
1	Hypoxia (Hypoxemia) 07/2013
1	Pancreatic Neoplasms (Pancreatic Cancer) 05/2013
1	Myeloid Leukemia (Leukemia, Myelocytic) 07/2011
1	Multiple Myeloma 03/2011
1	Melanoma (Melanoma, Malignant) 12/2010

Drug/Important Bio-Agent (IBA)

4	Phosphotransferases (Kinase)IBA 01/2018 - 03/2011
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2020 - 07/2011
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020 - 03/2011
3	tanshinoneIBA 03/2014 - 01/2010
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2013 - 01/2010
2	PowdersIBA 03/2020 - 01/2020
2	Biological ProductsIBA 01/2020 - 01/2018
2	Pharmaceutical PreparationsIBA 01/2020 - 05/2013
2	FlavonoidsIBA 01/2020 - 03/2011
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 01/2019
2	MelatoninIBA 02/2016 - 03/2012
2	bcr-abl Fusion ProteinsIBA 06/2014 - 05/2013
2	Cisplatin (Platino)FDA LinkGeneric 03/2012 - 11/2009
1	cyanidinIBA 03/2020
1	NF-kappa B (NF-kB)IBA 03/2020
1	Ethanol (Ethyl Alcohol)IBA 03/2020
1	Collagen Type I (Type I Collagen)IBA 01/2020
1	ampelopsinIBA 01/2020
1	CollagenIBA 01/2020
1	Connective Tissue Growth FactorIBA 01/2020
1	Adenosine Monophosphate (AMP)IBA 01/2020
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2020
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2019
1	Dextran SulfateIBA 01/2018
1	xanthohumolIBA 01/2018
1	CarbonIBA 01/2018
1	Chalcone (Benzalacetophenone)IBA 01/2018
1	Active Hexose Correlated CompoundIBA 01/2018
1	ginsenoside Rh2IBA 12/2017
1	Arsenic Trioxide (Trisenox)FDA Link 02/2016
1	Mechanistic Target of Rapamycin Complex 1IBA 02/2016
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 07/2015
1	Antineoplastic Agents (Antineoplastics)IBA 10/2014
1	Imatinib Mesylate (Gleevec)FDA Link 06/2014
1	1- (2- hydroxyethyl)- 3- (6- (2- methoxyphenyl)benzo(d)thiazol- 2- yl)ureaIBA 06/2014
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 03/2014
1	2- (2- chloro- 4- iodophenylamino)- N- cyclopropylmethoxy- 3,4- difluorobenzamideIBA 03/2014
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 03/2014
1	3-methyladenineIBA 03/2014
1	N- (5- (3- (3- cyanophenyl)imidazo(1,2- a)pyridin- 6- yl)pyridin- 3- yl)benzenesulfonamideIBA 07/2013
1	Caspase 3 (Caspase-3)IBA 07/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2013
1	BenzenesulfonamidesIBA 07/2013
1	LigandsIBA 05/2013
1	ethyl 6- (5- (phenylsulfonamido)pyridin- 3- yl)imidazo(1,2- a)pyridine- 3- carboxylateIBA 05/2013
1	5- ((6- phenyl- (1,2,4)triazolo(4,3- b)pyridazin- 3- yl)methyl)isoquinolin- 1(2H)- oneIBA 05/2013
1	Sorafenib (BAY 43-9006)FDA Link 05/2013
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2013
1	Proto-Oncogene Proteins c-metIBA 05/2013
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 05/2013
1	tyrosine receptor (receptor, tyrosine)IBA 05/2013
1	IPD-196IBA 02/2013
1	pyridineIBA 02/2013
1	JNK Mitogen-Activated Protein KinasesIBA 01/2013
1	Caspase 8 (Caspase-8)IBA 07/2011
1	cryptotanshinoneIBA 07/2011
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 03/2011
1	baohuoside IIBA 03/2011
1	PhosphoglucomutaseIBA 12/2010
1	activin AIBA 12/2010
1	AntioxidantsIBA 12/2010
1	sulforaphaneIBA 12/2010
1	Proteins (Proteins, Gene)FDA Link 12/2010
1	isothiocyanic acidIBA 12/2010
1	TubulinIBA 12/2010
1	TensinsIBA 01/2010
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2010
1	Phosphates (Orthophosphate)IBA 01/2010

Therapy/Procedure

3	Therapeutics 01/2018 - 01/2013
1	Oral Administration 10/2014